Publications

1. Lan, P. D., Nissley, D. A., Sitarik, I., Vu, Q. V., Jiang, Y., To, P., Xia, Y., Fried, S. D., Li, M. S., & OBrien, E. P. Synonymous Mutations Can Alter Protein Dimerization Through Localized Interface Misfolding Involving Self-entanglements. Journal of Molecular Biology 2024, 436(6), 168487 Read more

2. Halder, R.; Nissley, D. A.; Sitarik, I.; Jiang, Y.; Rao, Y.; Vu, Q. V; Li, M. S.; Pritchard, J.; O’Brien, E. P. How Soluble Misfolded Proteins Bypass Chaperones at the Molecular Level. Nat. Commun. 2023, 14 (1), 3689. Read more

3. Vu, Q. V; Nissley, D. A.; Jiang, Y.; O’Brien, E. P.; Li, M. S. Is Posttranslational Folding More Efficient Than Refolding from a Denatured State: A Computational Study. J. Phys. Chem. B 2023, 127 (21), 4761–4774. Read more

4. Vu, Q. V; Sitarik, I.; Jiang, Y.; Yadav, D.; Sharma, P.; Fried, S. D.; Li, M. S.; O’Brien, E. P. A Newly Identified Class of Protein Misfolding in All-atom Folding Simulations Consistent with Limited Proteolysis Mass Spectrometry. (In Review). PrePrint available

5. Leininger, S. E.; Rodriguez, J.; Vu, Q. V.; Jiang, Y.; Li, M. S.; Deutsch, C.; O’Brien, E. P. Ribosome Elongation Kinetics of Consecutively Charged Residues Are Coupled to Electrostatic Force. Biochemistry 2021, 60, 43, 3223–3235. Read more

6. Vu, Q. V.; Jiang, Y.; Li, M. S.; O’Brien, E. P. The Driving Force for Co-translational Protein Folding is Weaker In the Ribosome Vestibule due to Greater Water Ordering. Chemical Science 2021. 12, 11851-11857. Read more

7. Nissley, D. A.; Vu, Q. V.; Trovato, F.; Ahmed, N.; Jiang, Y.; Li, M. S.; O’Brien, E. P. Electrostatic Interactions Govern Extreme Nascent Protein Ejection Times from Ribosomes and Can Delay Ribosome Recycling. J. Am. Chem. Soc. 142, 13, 6103-6110 (2020). Read more